This section is from the book "A Treatise On Therapeutics, And Pharmacology Or Materia Medica Vol1", by George B. Wood. Also available from Amazon: Part 1 and Part 2.
This is made by adding muriatic acid, or a solution of chloride of sodium, to a solution of nitrate of silver. The chloride of silver is precipitated as a white curdy substance, which, when washed and dried, is ready for use. Though white at first, it soon begins to darken on exposure. It is insoluble in water. The circumstance that nitrate of silver is often converted into the chloride in the stomach, has led to the em ployment of the latter, as likely to produce the same effects on the system, while much less irritant. Many years since, I was induced myself, by this consideration, to try it in epilepsy; but, meeting with no encouraging success, I soon abandoned it. Dr. Perry used it in the Blockley Hospital of Philadelphia, and obtained advantage from it in chronic dysentery. It has been employed also in syphilis, and in other diseases in which the nitrate is recommended; but it has not come into general use. The dose is from one to three grains, or more, three or four times a day. Twelve grains have been given daily for three months, without unpleasant symptoms. A dose of thirty grains has produced vomiting.