Hops may be used as a tonic in dyspeptic or debilitated states of the digestive organs, and are specially indicated in cases attended with nervous restlessness and want of sleep. This condition not (infrequently exists in the convalescence from acute diseases, and in persons of a nervous temperament, who have been exposed to the influence of other debilitating causes. On any occasion of obstinate wakefulness, dependent on mere nervous disturbance, hops may bo tried among other means of relief, and especially when some objection may exist to the use of opiates. They are supposed sometimes to have operated usefully in the morbid vigilance of insanity. In all these et a dose of the infusion of hops, of lupulin, or, when stimulation is also indicated, of one of the tinctures, may be given three or four times a day.

But the case to which hops are probably most appropriate is that of the inebriate, suffering under the want of his accustomed stimulus. The medicine appears sometimes to operate most happily in such cases, in supporting the digestive function, controlling nervous tremors, obviating hallucinations, and disposing to sleep. Unassisted by stimulants, it is not adequate to supply the want of alcoholic drinks altogether; but, in the form of malt liquors, or that of the tincture of hops or of lupulin, it will, I believe, often enable the patient to escape the horrors of delirium tremens, with a smaller amount of alcoholic stimulus than would otherwise be necessary. In delirium tremens itself, the tincture is often an admirable adjuvant to opium; and I feel confident that I have seen sleep induced by it, in cases of this kind, which resisted the opiate treatment, without any reason for ascribing the result merely to the alcoholic ingredient. In convalescence, moreover, from that disease, it is one of our best remedies for sustaining a moderate tonic and soporific influence over the patient, until nature shall have recovered her powers. In these conditions, the tincture of lupulin may be given in the dose of half a fluid-ounce every two or three hours in the beginning, to be gradually diminished, and with lengthened intervals, as it may cease to be requisite, either for supporting strength, or producing sleep.

Dr. Maton found the medicine useful in allaying the pains of acute rheumatism; but it is vastly inferior to opium for this purpose.

It has occasionally been used in intermittent fever without very encouraging success; but has recently been recommended in that complaint by Dr. W. Y. Godberry, of Benton, Miss., as equal to any other article of the Materia Medica except quinia; and he has often succeeded in arresting the disease by means of it, after that medicine had failed. He prefers the infusion, which should be made with an ounce to a pint of boiling water; the whole to be taken during the intermission. (Am. Journ. of Med. Sci., N. S., xxvi. 283, from West. Journ. of Med. and Surg., March, 1853).

From the statements of Dr. Page before referred to, lupulin would appear to be one of the best remedies in our possession for relieving irritations of the genital organs in men. In the painful erections occurring in gonorrhoea, he gives it in doses of from five to ten grains, and has never known an instance in which the second dose did not afford relief He has also found it useful in spermatorrhoea; preventing the discharges while the patient is under its influence, though inadequate to the cure.

These statements of Dr. Page have been confirmed by subsequent observers. I have myself witnessed, in irritation of the urinary organs, very beneficial effects resulting apparently from the use of lupulin.