Sclerosis means hardened tissue. Tissue in that state is very feebly vascular. It is white, firm. and resistant, grating under the knife. Keloid, which is an exaggerated development of scar tissue, is a form of sclerosis. Cirrhosis of the liver is a type of sclerosis, and atrophy of the liver is another form.

Organs that have been hardened from inflammation sometimes take on compensatory hypertrophy (enlargements). Then is presented normal tissue endeavoring to replace hard tissue, and this modifies the form of the organ.

Fistulas are the result of a hardening of the walls of an opening through which pus has been discharging. Instead of the walls on an abscess closing and healing, a hardening of the walls takes place, and the result is fistula.

When urethritis has continued for months, the walls of the canal harden at those points where the inflammation has continued. The result is hardening or stricture. Stricture of the urethra may form with no more to irritate the mucous membrane than unusually strong urine from meat eating.

When an irritation has continued for months or years, as in continuous acidity of the stomach, a chronic inflammation is produced, enlarging, and then hardening. If the offense to the tissue is continued, the end of the degenerative process will be cancer. Cancer is a form of spontaneous gangrene. When tissues have hardened to such an extent as to cut off the oxygen supply, there is nothing left but dry atrophy. If, however, there are islands of tissue throughout the mass of atrophying hypertrophy which still receive nourishment, life will continue until the hardening encroaches on the inlets of food to such an extent that nourishment is shut off. Then decomposition takes place, with the development of toxins; following which comes, slowly but surely, systemic infection.

An acidosis of a subtle form may develop a general hardening of tissues. If the circulatory system is most involved, death will come from atheromatous diseases--arteritis, endocarditis, apoplexy, paralysis, or arteriosclerosis. If the glandular system is most involved, then tuberculosis may follow. If serous tissue is most involved, perhaps cancer will be the ending of life.

The probabilities are that when syphilis, tuberculosis, gangrene, sclerosis, hypertrophy, atrophy, and all the various forms of infections and so-called contagions, are understood, they will prove to be different forms of one and the same thing; namely, sclerosis--or infection, inflammation, gangrene, death; and the various causes are all different forms of one and the same thing. Multi-specific causations, followed by multi-specific effects, as a basis on which to build a rational theory and practice of healing, are so out of keeping with the teachings of science and philosophy that it is a continuous surprise that such a system can receive the endorsement and support of as large a body of intelligent professional men as are found banded together under the banner of modem medical science.

'The whole phenomenon or complex of life, health, and disease may be summed up in three words; namely; digestion, nutrition, infection.