When speaking of derangements of the pancreas, we necessarily, in this connection, think of digestion of the starches. If the mouthing of food is neglected, the whole work of digesting the starches falls on the alkaline secretions of the intestine. The pancreas stands at the head of this secretion. When there is difficulty in taking care of fat, we also think of a deranged secretion of the pancreas. The indication of deranged functioning of the pancreas is a changed appearance of the character of the stools. There is an excess of fat, which in some cases runs very high--even to one hundred per cent of the intake. The pancreatic secretion is necessary for the emulsifying of fat. When fats are not emulsified, they do not pass through the walls of the intestine; or, in other words, they are not absorbed and not utilized as food. The carbohydrates also fail of digestion, and the stools show a waste of these foods. When there is a failure in intestinal digestion, there is, accompanying this failure, colitis, because, if these foods are not digested, they go through an acetous and putrefactive change, which develops toxins, which are absorbed, and create irritation and inflammation of the mucous membrane of the intestine. Hence the importance of the pancreatic secretion may be seen in warding off the primary cause, not only of inflammation of the intestinal mucous membrane, but also of the diseases created by the absorbed toxins, as well as those that come from imperfect digestion of sugar, such as diabetes.