Colic is a very common affection of infancy. It usually occurs in the period between birth and the end of the third month, and gives rise to much discomfort, both to the infant and its attendants, by causing fretfulness, crying and wakefulness. The treatment is very much one of careful regulations of the diet. Still, there are some domestic remedies which may be used safely and with success. Thus, the abdomen should be anointed twice a day with warm olive oil and enveloped in a broad flannel binder. It is even more important to keep the feet warm, and for this purpose thick socks or long woolen stockings should be worn, and, in bad cases, artificial heat must be applied by hot-water bottles. Medicines are indicated chiefly during attacks of pain. A serviceable prescription is ten drops of gin in a teaspoonful of sweetened warm water, or a small teaspoonful of hot soda-mint. It is also well to administer five to ten drops of essence of pepsin or of diazyme essence after each nursing. When a paroxysm of pain is violent enough to lead to depression of the fontanelle and threaten collapse, place the infant in a warm bath for five minutes. After removing and carefully drying him, wrap him in a blanket; put a flax-seed poultice with a little mustard flour over the abdomen; apply a hot-water bottle to the feet; relieve the bowels by an enema of warm saline solution, and by the mouth give him ten drops of gin or brandy in warm water. If the fontanelle still remains depressed, continue the stimulant in doses and at intervals proportioned to the urgency of the symptoms.