Crataegus Oxyacantha, English Hawthorn Fruit. This remedy is of too recent introduction to speak positively regarding it. Very enthusiastic reports are appearing favoring it as an improvement over digitalis in the treatment of heart disease. It is beneficial in chronic heart affections with a weak and irregular action. What more can be affirmed of it time will tell. Dose, f.e., 5 to 10 I.. If for long-continued administration, tr., 8 to 15 I.

"Creolin," "Cresol," "Lysol," Crude Carbolic Acid, ETC.

The new U. S. Pharmacopceia drops crude carbolic acid, calls purified carbolic acid "Phenol," and makes official "Cresol"

The heavy oil of coal tar, which distils over at from 325 to 3750 Fahr., is the usual source of these products. Crude carbolic acid is a very complex substance, containing "Phenol" and three isomeric cresols, hydrocarbons, and water. For many uses as a disinfectant it is just as serviceable and is much more economical than "Cresol." "Cresol" is the combination of the three isomeric cresols, and contains no phenol. It may be given internally in doses of I or 2 drops, well diluted. It is much more expensive than crude carbolic acid, and is to be preferred in surgical work. "Creolin" is practically saponified cresol. It is described as "saponified coal-tar creosote." Its advantage consists in being in such a state as to form at once an imperfect admixture with water. One fluidounce to a gallon is its usually employed aqueous mixture. Its disadvantage is that the mixture is turbid.

"Lysol" is a 50% creosol product, the cresylic acid being in a free and soluble state. Its aqueous solution is clear. It is used in 0 to 2% solution in surgery. Its disadvantage is that hands and instruments immersed in it are slippy. Bichloride solution washes the slippy coating off the hands.

All of these agents are of much greater bactericidal power than phenol, and they are rapidly displacing it in surgery.