This section is from the book "A Practitioner's Handbook Of Materia Medica And Therapeutics", by Thos. S. Blair. Also available from Amazon: A Practitioner's handbook of Materia Medica and Therapeutics.
Hyoscine and Hyoscine Hydrobromate have a similar action to hyoscyamine, and are usually preferred to it. The use of these latter agents is principally to quiet insane persons.
A sane person should be given doses of 1-400 to 1-200 grain of hyoscine or its salt, while an insane man may readily tolerate 1-30 gr.