This section is from the book "A Practitioner's Handbook Of Materia Medica And Therapeutics", by Thos. S. Blair. Also available from Amazon: A Practitioner's handbook of Materia Medica and Therapeutics.
Hyoscyamine, as employed in medicine, is commonly made from hyoscyamus, but is similar to that separated with much more difficulty from belladonna. It is employed as a hypnotic, mydriatic, and sedative in doses of 1-120 to 1-30 gr. The sulphate is employed in similar doses.