Nux Vomica. For the discussion of this important drug in detail see larger text-book.

In large doses (2 to 5 gr.; extract, 1/2 gr.; f.e., 4 I.; U. S. P. tincture, 20 I.) it is a powerful respiratory and nerve stimulant, useful in poisoning by narcotics, acute heart failure, marked nervous prostration, many cases of subnormal temperature, flaccid paralyses without central irritation, surgical shock, and in the treatment of dipsomania.

Strychnine or its sulphate is frequently to be preferred to nux vomica in these conditions, since it is quicker in action and suitable for hypodermic injection without elaborate preparation of sterile solutions. Dose, I -30 to I - 15 gr.

In moderate doses (I to 2 gr.; extract, 1/8 to 1/4 gr.; f.e., I to I 1/2 I; tr., 6 to 10 I. ; strychnine, I -60 to 1-40 gr.) it is indicated in many conditions demanding a stimulant tonic to the nervous and circulatory systems in convalescence, sexual exhaustion, and impotence, and in acute digestive disturbances. In small doses (tr. 1 to 3 I, or the first dilution) it is adapted to two classes of cases. The first class is the patient with a sallow skin, especially around the mouth, a dead-looking more or less yellow conjunctiva, pasty yellow coat upon the tongue, abdominal fullness and torpor, and cramp at times in the umbilical region. The second class is the patient who is thin, nervous, and irritable, living under a strain, with business cares and long hours, uses tobacco and stimulants, eats heavy food, loses sleep, and develops nervous dyspepsia, portal congestion, and more or less hypersensitiveness. The 2x tablet triturates act well in these cases. Small doses of nux vomica are highly useful, but minute doses of strychnine do not do so well, since its action is largely expended upon the spinal cord and not upon the viscera.