Nicotiana Tabacum, Tobacco. This agent is too irregular in action to be a safe internal remedy. Squibb's Nicotine is a nerve sedative and relaxant of value in strychnine poisoning in doses of I -64 to 1-20 gr. once or twice a day in solution. One dram of Scotch snuff to 1 K of vaseline is useful locally in muscular rigidity, incarcerated hernia, and bronchial spasm.