This section is from the book "A Practitioner's Handbook Of Materia Medica And Therapeutics", by Thos. S. Blair. Also available from Amazon: A Practitioner's handbook of Materia Medica and Therapeutics.
Paeonia is employed in 2X and 3X in rectal irritation and itching, as well as in fissures and hemorrhoids. It is asserted to relieve the pain, but is not used to the exclusion of local treatment. Large doses cause vertigo and diarrhea.