This section is from the book "A Practitioner's Handbook Of Materia Medica And Therapeutics", by Thos. S. Blair. Also available from Amazon: A Practitioner's handbook of Materia Medica and Therapeutics.
Stillingia, Queen's Root. In large doses is emetic and cathartic, causing gastro-enteric irritation and prostration. Pharmaceutically, stillingia presents the difficulty of the red tannates, and its preparations are liable to be either inert or to readily disintegrate. While the dried root is active. the recent root is far preferable. The present writer has used stillingia very largely, and believes a decoction of the recently dried root to be a most potent vegetable alterative. Several makes of f.e. and the ec. tr. and N. F. tr. are reliable, but the U. S. P. average dose of 30 I. is too high when reliable preparations are used. One-third of this amount is quite effective, and may be long continued without irritation. To me it is exceedingly annoying that the revisers of the U. S. P. do not take more into consideration the many statements in the U. S. and National Dispensatories as to the differences between recent and old herbs and roots. A great many instances are noted in these most excellent works where long-continued drying is deleterious to or ruins the drug. Stillingia is an instance.
As a matter of fact, when we write for fluidextract of stillingia, U. S. P., it is purely a guess whether we will get an active drug or an inert mess. There exists not one scientific reason why the U. S. P. should ignore the chemical and botanical data of the dispensatories. It is certainly to be hoped that the U. S. P. preparations of the large class of drugs, of which stillingia is a type, will, at the next revision, be placed upon some reasonable basis of requirements as to the state of the crude drug.
Physicians who have never properly exhibited Stillingia have little idea of its great value. In small doses, long administered, we have a. remedy in secondary syphilis, scrofula, lymphatic and glandular troubles, and chronic skin and throat troubles truly second only to the iodides.