Drugs reach the system:

1. By absorption from the stomach and intestines after their administration by the mouth in liquids, powders, wafers, tablets, pills, or capsules.

2. By absorption from the rectum after their administration as enemata or suppositories.

3. By absorption from the skin after their inunction or after prolonged contact with the skin.

4. By absorption from the mucous membranes when they are brought into contact with them.

5. By absorption from the subcutaneous tissues after their injection with the hypodermic syringe.

6. By absorption from the deep muscular tissue after deep injection with a long hypodermic needle.

7. By being directly introduced into the blood stream by intravenous injection.

The rapidity of absorption and action, and the size of the dose, varies with the method and route of administration.

The Rapidity of the Absorption of a drug is in the following order, the quickest route heading the list:

When given intravenously.

When given hypodermatically.

When brought into contact with mucous membranes, es-peciallv of the nose.

When given by the stomach.

When given by the rectum.

When given by the skin.

The most prolonged action of a drug would be in the inverse order of the list just given. The size of the dose would be in the same order as the list, with the smallest.