This section is from the book "Dental Medicine. A Manual Of Dental Materia Medica And Therapeutics", by Ferdinand J. S. Gorgas. Also available from Amazon: Dental Medicine.
Sulphate of Cadmium is obtained by the action of nitric acid, diluted with distilled water, on the metal cadmium, the solution filtered and mixed with carbonate of soda, and again dissolved in sulphuric acid diluted with distilled water. It is in the form of transparent, colorless crystals, like those of sulphate of zinc.
Sulphate of cadmium is emetic and astringent, and closely resembles sulphate of zinc in its action, but is stronger, with a caustic astringent taste. It is very nauseant and depresses greatly. Locally it is an irritant poison, and produces the cerebro-spinal symptoms of coma and convulsions; it is not administered internally, as the preparations of zinc are preferable for such use.
Sulphate of cadmium is employed locally in affections of the eye, being valuable as a collyrium; it has the power of causing absorption of opacities of the cornea to a remarkable degree. It is also used as an injection in gonorrhoea, in the strength of one grain to four ounces of water. It is also used in the form of ointment, two grains with four scruples of lard.
Sulphate of cadmium has been employed in ulcerations of mucous membrane, gangrene of the mouth, or can-crum oris, indolent ulcers, purulent diseases of the antrum, in the form of injections and lotions, of a strength about one grain of the sulphate to four ounces of water.