By the direct combination of the metal with iodine in the presence of water.

Characters And Tests

Occurs in flat, micaceous white crystals, of pearly lustre, which melt at 600° F. into an amber-colored fluid; they are anhydrous, permanent in air, but decompose at a dull-red heat, with evolution of iodine in vapor. In water and spirit they are freely soluble, the solution being acid to test paper, and answering to the tests for cadmium already mentioned.

The Sulphate of Cadmium is officinal in the United States. It occurs in oblique, rhombic prisms, translucent and colorless, like those of zinc sulphate; it has an acid, astringent taste, effloresces on exposure, and dissolves readily in water.

The Bromide of Cadmium resembles the analogous salt of ammonium, and has been taken by mistake for it; it is used in photography.

Absorption And Elimination

Cadmium salts coagulate and combine with albumen, but these albuminates dissolve in an excess of the salt, especially in excess of a double salt, such as the chloride of cadmium and sodium; even in alkaline chlorides they are partially soluble, so that we can readily understand their absorption from the stomach. Absorption occurs also after their injection into the cellular tissue, the bowel, etc., as evidenced by the finding of cadmium compounds in the organs and secretions (Marme: Schmidt's Jahrb., iii., 1867).

Elimination of the drug begins soon after its administration, and takes place mainly by the kidneys.

Physiological Action (Internal)