Foret has described, in cases of poisoning by cadmium carbonate, besides the symptoms of gastric irritation - giddiness, prostration, loss of consciousness, cramp, and slowing of respiration and heart-action. In the ladies above mentioned, somnolence was marked after subsidence of the irritant symptoms.

Synergists

Salts of zinc and lead.

Antidotes

In acute poisoning by cadmium salts, the alkaline carbonates with albumen (white of egg) are the best antidotes. In Marme's experiments, injections of dilute soda solutions into the stomach soon after the exhibition of the poison quite prevented bad effects.

Therapeutical Action (External)

The only officinal salt, the iodide, is used in the form of ointment in glandular scrofulosis, and has been recommended by Guibert and Garrod. Other physicians have prescribed it in splenic enlargement and in strumous skin disease (Waring). I have used it repeatedly in cases of enlarged glands, of nodes, and of chronic joint inflammation, with satisfactory result. It does not stain the skin, like iodide of lead, but is liable to cause irritation unless diluted.

In Ophthalmic Surgery cadmium sulphate has been used more as an astringent in lotion or ointment for dyscrasic inflammation of the eye, and for corneal opacities (leucoma), (Grafe, Kopp, Middlemore).

Therapeutical Action (Internal)

The sulphate of cadmium has been recommended in syphilis, rheumatism, and gout (Grimand), but there is, at present, little evidence of its special powers.