Cadmium compounds, except the sulphide, resemble each other in action. The sulphide, though considered poisonous by van Hasselt, has been given to animals in drachm doses daily for a week, without evident effect, and is therefore pronounced inert by Marme. The oxide, chloride, sulphate, iodide, etc., given in doses of 1/2 to 2 gr., cause pain at the epigastrium, vomiting, and purging, and in somewhat larger doses gastro-enteritis, which may pass on to ulceration. Similar effects follow their hypodermic injection, and after toxic doses given in this manner, the gastro-intestinal mucous membrane has been found inflamed; irritation and suppuration also occur at the site of injection. The continued administration of small doses induces a chronic form of poisoning marked by dyspepsia and emaciation, which in animals has terminated in death from exhaustion. In the case of two ladies who took by accident a quantity of bromide of cadmium (not less than 5, or more than 16 gr). pungent taste and sensations in mouth and throat were felt, and burning pain at the epigastrium, vomiting and purging set in, and continued for five hours, and after recovery the stomach remained very irritable (Wheeler: Boston Medical and Surgical Journal, October, 1876). In a man who took 9 gr. of a cadmium salt, salivation, colic, and catharsis followed in the course of an hour, and four hours afterward, violent vomiting, gastralgia, and tenesmus (Burdach). In a dog, death has followed the injection of 1/6 to 1/3 gr. into a vein, or the giving of 5 to 9 gr. by the mouth.