Many other drugs have an action somewhat similar to that of curare upon the motor nerves :Ammonium cyanide.1

„ iodide.

Ethyl ammonium chloride.1 Amyl ammonium chloride.1

„ „ iodide.1

Amyl ammonium sulphate.1 Phenyl - di - methyl - ethyl ammonium iodide.13 Phenyl - di - methyl - amyl ammonium iodide.13 Phenyl - di - methyl - amyl ammonium hydrate.13 Phenyl-tri-ethyl ammonium iodide.13 Tri-methyl ammonium iodide.2 Tri-ethyl „ chloride.

„ „ iodide.

,, ,, sulphate.

Methyl-tri-ethyl stibonium iodide.14 Methyl-tri-ethyl „ hydrate.14

Toluyl-tri-ethyl ammonium iodide.13 Di-toluyl-di-ethyl „ „ 13

Toluyl-di-ethyl-amyl „ „ 13

Toluyl-tri-ethyl „ hydrate.13

Tetra-methyl „ iodide.

Tetra-ethyl ,, ,,

Tetra-methyl „ iodide.13

Tetra-amyl „ „ 13

Tetra-ethyl phosphonium iodide.14 Tetra-ethyl arsonium iodide.14 Tetra-ethyl arsonium and zinc double iodide.14

Tetra-ethyl arsonium and cadmium double iodide.14

Anchusa.3

Methyl anilin.4

Ethyl „ 4

Amyl „ 4

Methyl-atropine.2

Methyl-brucine.2

Ethyl-brucine.3

Camphor.

Methyl-cinchonine.3

Amyl „ 3

Chloroxethylene.

Methyl-codeine.2

Collidine.

Coniine.

Di-methyl-coniine.2

Cotarnine.3

Cynaglossine.5

Di-methyl ammonium chloride.1 ,, ,, iodide.1

„ „ sulphate.1

Di-ethyl ,, chloride.1

,, ,, iodide.1

„ ,, sulphate.1

Curarine.6

Curare.7

Ditaine.8

Methyl-delphinine.3

Echium.3

Erythrina corallodendron.9

1 Brunton and Cash, Proc. Roy. Soc.

2 Crum-Brown and Fraser, Trans. of Roy. Soc. of Edinburgh.

3 Buchheim and Loos, Eckhard's Beitrage, Bd. v.

4 Jolyet and Cahours, Compt. Rend., lxvi. p. 1181.

5 Diedulin, Med. Centralbl., 1868, p. 211.

6 Preyer, Gottinger Ztschr. f. Chemie, 1, p. 381. 7 Bernard and Kolliker.

8 Harnack, Arch. f. exp. Path. u. Pharm., vii. p. 126.

Guachamaeha.10 Lobeline.

Methyl-morphine.2 Methyl-nicotine.2 Ethyl „ 3

Ptomaines.11 Methyl-quinine.3 „ quinidine.2

Methyl-piperidine.

Saponine.

Sparteine.

Methyl-stryclinine.2, 12 Ethyl „ 2

Methyl-thebaine.2 Methyl-veratrine.3 Amyl „ 3

Although the substances mentioned in the above list have all the power of paralysing motor nerves, they do not possess the same power as curare. In the case of the salts of ammonium and the compound ammonias, the curare-like action is accompanied by a paralysing effect upon the muscular substance and on the nerve-centres. When salts of these substances are employed, their effect is somewhat modified by their acid radical, although this is not the case to the same extent in the salts of the compound ammonias, and in the salts of ammonium itself. Thus the iodide of ammonium has a much stronger paralysing action on the nerves than bromide, chloride, sulphate, or phosphate, and this is observed also, though to a less extent, in the salts of the compound ammonias.1