This section is from the book "Materia Medica Pharmacy, Pharmacology And Therapeutics", by W. Hale White. Also available from Amazon: Materia Medica Pharmacy, Pharmacology And Therapeutics..
(Not official.) - 2C9H10N(Och3)H2So4 +2H2O=459.06.
By heating together Paramidoanisol, Paranitranisol, Glycerin and Sulphuric Acid.
A white or whitish granular crystalline powder having a slightly Anise-like odor and a nauseous, bitter, saline and pungent taste. Solubility. - In 7 parts of water; in 100 parts of Alcohol.
Dose, 2 to 10 gr.; .12 to .60 gm.
This drug was introduced into medicine as an antipyretic, but it was soon abandoned because of the dangerous collapse with marked cyanosis which it produced. It is rarely given internally, because it is poisonous to the red blood corpuscles and to the nervous system. Its chief use is as an injection for gonorrhoea, in aqueous solution (1 or 2 to 120), or it can be used in a 2 per cent. solution in gelatin bougies. In gleet beneficial results have followed the injection of 1 to 8 aqueous solutions.
 
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