This section is from the book "Practical Materia Medica And Prescription Writing", by Oscar W. Bethea. Also available from Amazon: Practical Materia Medica and Prescription Writing.
The quantity is too large and the dosage not sufficiently intense for an acute condition.

Lemonade is often a desirable diluent for a remedy of this type.
In using a combination of this character the prescriber should have patient sufficiently under observation to enable him to discontinue the medicine at the proper time.
The trend of the profession is toward the employment of water as the one great antipyretic.
First prescription for a patient with high blood-pressure, and urine with low specific gravity.

The nitrate is not the salt desired.
Large doses of sodium nitrite should never be used until the effect of smaller doses has been noted.
A small bottle containing a smaller dose would be indicated to begin the treatment.
Iodi is the genitive for iodine, but not for iodide.

Note that the attention of the compounder is called to the word nitritis, which closely resembles nitratis.
The direction "in a glass" is changed to "with a glass." The patient often can better take a dose with a small amount of the diluent ordered and use the rest to remove the taste from the mouth, in preference to drinking a whole glass of a disagreeable mixture. The dilution in the stomach is the same, of course.
It is often more desirable to give a preparation of this type with water.
Prescribed for a patient suffering from anemia, loss of appetite, general weakness, etc.

In a prescription of this type it is better to list the ingredients in the order in which they should be mixed. Nux vomica added to tincture of ferric chloride would cause a precipitate of iron tannate.
If the phosphoric acid is added to the iron first the reaction does not take place.
Nux in the genitive changes to nucis.
The directions would be better if transposed.

Attention is called to the instructions that the preparation be taken in water. Dilution lessens the action on the teeth, renders the taste less disagreeable, and aids the action as a bitter tonic.
In ordering an iron solution the physician should always instruct that the preparation be taken through a tube and the teeth cleansed after each dose.
The following "Four Chlorides" tonic is often prescribed.

"Mrs. Sam" may be objectionable.
The mercuric salt being a solid, a potent drug and one of the principal ingredients, should be written first.
The arsenic solution, as the most potent and probably important of the liquids, should be written before the others.
There is no reason why this should not be concentrated to a 6-ounce solution with teaspoonful dose.

It is particularly desirable in prescribing preparations as the above to give the patient written instructions as to the amount of water to use, the time of taking, the use of a glass tube, and the cleaning of the teeth after each dose.

Prescribed as an agreeable quinine preparation for a child.
The principle in preparing so-called "tasteless" quinine is to use a salt that will dissolve only to the smallest possible extent so that it will not come into contact with the special nerve elements in such form as to be appreciated.
The age of the patient should be given.
Liquorici is not the proper name of the drug wanted.
The vehicle should be used in sufficient quantity to make up to 2 fluidounces.
The sulphate is probably the best salt for "tasteless" quinine mixtures. The tannate is the least bitter of the quinine salts, but has to be given in larger amounts and at least is slower and more uncertain in action.
It is usually possible to ascertain the preference of the child as to flavor. Glycyrrhiza may be distinctly disagreeable to some, while syrup of chocolate would be very agreeable.
Written instructions may be given as to shaking the mixture.

Used as a tonic particularly in chronic malaria.
Liquor Arseni Chlor-idi and Tinctura Ferri are not the proper names for the preparations wanted.
It is unnecessary to use distilled water in a preparation of this character.
ad may well be omitted.
The directions are subject to improvement.
Physician's name should be more carefully written.


Where the condition was not malarial the amount of quinine sulphate would probably be reduced.
Written instructions should be given patient as to amount of water, use of glass tube, cleaning teeth, etc.
It should be remembered that a quinine solution is always intensely bitter and that patients are apt to discontinue the remedy.

Prescribed for indigestion.
Pepsini here calls for the U. S. P. product, which is standardized at 1 to 3000; so further specification is unnecessary.
Acidi Hyd. Dil. might mean the diluted hydrochloric, hydrobromic, hydrocyanic or others.
The label should indicate that the preparation is to be diluted for administration.
It should be remembered that a preparation of this character without instructions as to diet, manner of eating, etc., is practically useless.
It is probably best to discontinue the use of the pepsin preparation gradually. It may be first omitted after the lightest meal of the day, then used only after the principal meal, etc.

 
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