The Termination Of Inflammation depends upon the degree of inflammation and the amount of damage done. It may occur by resolution. This takes place only when the inflammation has been slight. The exudate is taken up by the lymphatics and returned to the circulation. Any degenerated cells will be taken up by the wandering leukocytes and the tissue will resume its normal condition.

In suppuration the inflammation has been destructive; there is actual loss of tissue, with the formation of pus.

As pus is formed it is either confined as an abscess or else it tends to infiltrate the tissues. In either case the tissues attempt to get rid of the irritating substance by having it follow along the least resistant paths and letting it escape from the body. This process of extension is known as "burrowing;" it results from the increased pressure due to the presence of the pus and to the digestive powers of the enzymes contained within.

In some cases the pus may quickly escape to the surface of the body and be cast off. It may, however, have to burrow a long distance, as in a psoas abscess, before it can escape.

Sometimes the pus may gain entrance into one of the cavities of the body, as the peritoneum or pleura, and give rise to inflammatory conditions there.

According to the cavity involved, the condition has special names. Empyema is pus within a pleural cavity; pyoperi-cardium when within the pericardial sac; pyosalpinx when a Fallopian tube is involved, etc.

Encapsulation is what takes place when the irritating material cannot be removed from the body. The surrounding tissue cells undergo multiplication and the substance is isolated by the formation of a connective-tissue capsule about it.

Organization is the process of repair by means of which the destroyed areas are filled up by connective tissue. It is not a case of the transformation of the inflammatory products into connective tissue, but is a condition of replacing. This new formation of connective tissue is known as a cicatrix or scar, the process as cicatrization.

The cells present in the repair of inflammation are derived from various sources, and consequently differ among themselves.

The leukocytes that form the greatest numbers are derived from the blood and are chiefly of the polymorphonuclear variety.