When there is a stone, or stones in the gall-bladder, which prevents the gall from running into the guts, by plugging up the passage; then there is a constant heavy fixed pain on the right side about the region of the liver, which sometimes reaches to the pit of the stomach. This pain is sometimes so exasperated, that the gripes and torture affect: all the inward parts of the belly. Add to these, a want of appetite, a reaching to vomit, a pain in the stomach, anxiety about the heart, and costiveness. This is succeeded by a jaundice, and in length of time a dropsy. In the fit, it will be proper to bleed in the arm; then give the following potion: "Take two ounces of manna, an ounce "and half of oil of sweet almonds, a dram and half of cream "of tartar, twelve drains of purified nitre; mix them." Let the patient take it by spoonfuls, at proper distances of time in the morning; or, the patient may take oil of sweet almonds alone; or a dram of sperma ceti, dissolved in broth, or syrup of marsh mallows, or whatever else is soft, oily, and emollient. Out of the fit, the best remedies are, soap, quicksilver, and salt water. Half a dram of Alicant soap may be taken fix times a day, made into pills. Half an ounce of quicksilver may be rub'd in a glass mortar, with half an ounce of brown sugar candy, and sixteen drops of essential oil of juniper berries, till it disappears; twenty grains of this may be given at night, mixt with twelve grains of sperma ceti, and twenty of conserve of mallow flowers, and be repeated every other night, several times. The patient may likewise be purged, now and then, with an ounce of Epsom salt, omitting the other things on the same day. Or half a pint of sea water may be given early every morning, for some time, after the soap and quicksilver have been left off.