Baptisia Tinctoria, Wild Indigo. In large doses baptisia causes emesis and purgation, but is not an acceptable remedy in large dose. The preparations of the green or recent plant should be employed. Locally applied, baptisia has long been used in aphthae and gangrenous sores. In small doses (ec. tr. I to 3 I., @ 3 to 10 I., if continuously administered in smaller doses) it is useful in typhoid conditions if administered very early in the disease. This is due to its antiseptic qualities and its influence upon the intestinal glands. For the same reason it is useful in dysentery with dark, fetid discharges. It appears to oppose gangrenous tendencies, and has therefore been used in malignant forms of laryngitis, but the evidence in its favor in this direction is not very positive. Homeopathic physicians esteem this drug very highly, and use it in very much smaller doses than those noted here. For this reason I have very carefully watched its influence in the many cases in which I have used it. As to dose, I fail to get results in doses less than I minim of the tincture. It surely does have a marked influence in low fevers and in gastro-intestinal troubles with a tendency toward putridity. In conditions characterized by dark or purplish mucous membranes, dry and darkly coated tongue, and a dusky face with feeble circulation, the drug is useful and ofttimes highly valuable, but it can in no sense of the word be regarded as the sole or mainstay in typhoid fever. The drug is an antiseptic, alterative, and antizymotic, and has no especial influence upon the febrile process. Within its proper indications it is a valuable auxiliarv to the more direct medication necessary for specific conditions. Begun early and steadily persisted in, it does much good, but is of little value when first given in advanced stages of disease.