Homatropinje Hydrobromidum. This agent is seldom employed internally. The U. S. P. wisely gives its dose as 1-128 gr. (average). This is safe, but it has been advised in I -20 gr. for excessive night sweats. In regard to this, it may be said that it takes doses verging upon the toxic to control severe night sweats with any of the belladonna derivatives. On the other hand, the experience of some of the tuberculosis sanitoria is that proper diet and fresh air render such agents almost unnecessary. Personally, I have frequently controlled excessive sweats with small doses of muscarine in some form. In the determination of refraction in ophthalmic practice this mydriatic is prompt but evanescent. Use 4 gr. to the ounce of distilled water.