Elizabeth Of Valois, Or Isabella, queen of Spain, born at Fontainebleau, April 13, 1545, died in Madrid, Oct. 3, 1568. She was a daughter of Henry II. and Catharine de' Medici. By a treaty concluded at Angers in 1551 she was betrothed to Edward VI. of England, but the marriage was prevented by his premature death. By the preliminaries of the treaty of peace of Cateau-Cambresis, her hand was assigned to Don Carlos, infante of Spain. The treaty was ratified April 3, 1559; but the father of Don Carlos, Philip II., being left a widower by the death of his wife, Queen Mary of England, and fascinated by a portrait which he had seen of the French princess, substituted himself for his son. After a wedding by proxy celebrated at Paris in June, she was united to Philip in February, 1560, the marriage ceremony being performed with great splendor at Toledo. Just before her death she was delivered of a daughter, who lived only to be baptized and was buried in the same coffin with her mother. Romantic accounts have been given of the relations between Elizabeth and Carlos, but Prescott in his "History of the Reign of Philip II." proves their groundlessness.