I

Apply over the affected skin a solution of corrosive sublimate, 1 in 500, or, if the patient can stand it, 1 in 300, morning and evening, and for the night apply emplastrum hydrargyri compositum to the spots. In the morning remove the plaster and all remnants of it by rubbing fresh butter or cold cream over the spots.

For redness of the skin apply each other day zinc oxide ointment or ointment of bismuth subnitrate.

II

Besnier recommends removal of the mercurial ointment with green soap, and the use, at night, of an ointment composed of vaseline and Vigo's plaster (emplastrum hydrargyri compositum), in equal parts. In the morning wash off with soap and warm water, and apply the following:

Vaseline, white...... 20 parts

Bismuth carbonate... 5 parts

Kaolin............. 5 parts

Mix, and make an ointment.

III

Leloir has found the following of service. Clean the affected part with green soap or with alcohol, and then apply several coats of the following:

Acid chrysophanic .. 15 parts Chloroform........ 100 parts

Mix. Apply with a camel's-hair pencil.

When the application dries thoroughly, go over it with a layer of traumaticine. This application will loosen itself in several days, when the process should be repeated.

IV

When the skin is only slightly discolored use a pomade of salicylic acid, or apply the following:

Acid chrysophanic, from........... 1 to 4 parts

Acid salicylic...... 1 to 2 parts

Collodion.........         40 parts

V

When there is need for a more complicated treatment, the following is used:

(a)   Corrosive sublimate          1 part

Orange- flower water.......... 7,500 parts

Acid, hydrochloric, dilute.........         500 parts

(b)  Bitter almonds. ... 4,500 parts

Glycerine......... 2,500 parts

Orange-flower water..........25,000 parts

Rub up to an emulsion in a porcelain capsule. Filter and add, drop by drop, and under constant stirring, 5 grams of tincture of benzoin. Finally mix the two solutions, adding the second to the first.

This preparation is applied with a sponge, on retiring, to the affected places, and allowed to dry on.

VI

According to Brocq the following should be penciled over the affected spots:

Fresh pure milk......   50 parts

Glycerine...........   30 parts

Acid, hydrochloric, concentrated......     5 parts

Ammonium chlorate.     3 parts

VII

Other external remedies that may be used are lactic acid diluted with 3 volumes of water, applied with a glass rod; dilute nitric acid, and, finally, peroxide of hydrogen, which last is a very powerful agent. Should it cause too much inflammation, the latter may be assuaged by using an ointment of zinc oxide or bismuth subnitrate—or one may use the following:

Kaolin.............     4 parts

Vaseline............   10 parts

Glycerine...........     4 parts

Magnesium carbonate    2 parts

Zinc oxide..........     2 parts