This section is from the book "The Home Hand-Book of Domestic Hygiene and Rational Medicine. Volume 2.", by J. H. Kellogg, M.D.. Also available from Amazon: The Home Hand-Book of Domestic Hygiene and Rational Medicine, Volume 2.
Gradual darkening of the skin to bronze color, sometimes green or black; most intense on exposed parts; the roots of the nails and whites of the eyes remain uncolored; black spots on lips and mouth; great and increasing debility, and great depression; pain in the back and at the pit of the stomach; dyspepsia and vomiting; diarrhea; convulsions; rapid pulse, but no fever.
This is a very peculiar disease, and is named after the man who first described it. The symptoms which characterize the disease are supposed to be due to chronic inflammation and degeneration of the supra-renal capsules. The cause of the disease is not known.
The only treatment which is of any value whatever is the employment of such measures as will improve the patient's general nutrition and enable him to tolerate the disease as long as possible, recovery rarely, if ever, taking place.