Formula

C26H26(OI)2.

Derivation

Aristol is obtained by adding a solution of iodine in iodide of potassium, to an equal solution of hydrate of sodium, containing thymol. It is in the form of a red-brown, precipitated, amorphous, non-crystallizable powder. The proportion of iodine in aristol has been estimated by Carius at 45.80 per cent. Aris-tol is insoluble in water and glycerine, slightly soluble in alcohol, but readily soluble in chloroform, ether, and in the essential oils; but the solution must be made by friction without heat, as the aristol is decomposed by heat and also by the light. It possesses but a slight odor, like that of thymol, and is not unpleasant.

Medical Properties And Therapeutic Uses

Aristol possesses no irritant action upon the unbroken skin, and when applied to mucous membrane it promotes absorption. Not being absorbed, it has no toxic effect, and for such reason, together with its freedom from disagreeable odor, it possesses a great advantage over iodoform. It produces rapid healing, and has been employed with benefit in varicose ulcers as a dusting powder; also in cutaneous diseases, gonorrhoea, gleet, in operations of anal fistula, abscess, lymphadentitis, periostitis, psoriasis, ulcers, etc., etc. It is chiefly employed as a dusting powder, or in ethereal solutions or ointments, for epithelioma, burns and scalds. Aristol is considered to be an excellent and prompt antiseptic, but the name is merely an assumed one for dithymoldic iodine. Impurities in aristol would be all the by-products derived from unskillful treatment; it might contain potassium, or sodium iodide, or free iodine; it might be adulterated even, for, as a patented article, it is above control, as patents have been granted by the U. S. Patent Office for its control, manufacture and sale under the name of "aristol," being a compound of thymol with iodine. The virtue of aristol over iodoform, etc., has not as yet been so pronounced as to exclude it from the general class of patented medicines.

Dental Use

Aristol has been used as a substitute for iodoform, iodol, carbolic acid, etc., etc., in all cases when the ordinary antiseptics are indicated, as in gangrenous pulps, antisepticizing of root-canals, disinfection of cavities before the introduction of fillings, in the form of a 10 per cent. solution in sulphuric ether for disinfecting purposes; for gangrenous pulps, the aristol in powdered form may be applied with a small brush. Sticks made of cacao butter 10 parts, and aristol 1 part, may be used to promote granulation and healing. Aristol has the advantage of being effective in small quantities, and may be diluted with sugar of milk.

Dr. E. C. Kirk highly recommends aristol for aveolar pyorrhoea, a 10 per cent. solution being rubbed upon a glass plate with oil of cinnamon and introduced into each suppurating pocket, and around the root at the base of each pocket, on threads of absorbent cotton saturated with the solution ; the oil of gaultheria may be substituted for the oil of cinnamon if desired. Dr. Kirk and others also recommend aristol in the essential oils as a medicament for canal-dressings, and as a topical dressing in acute pulpitis. Dr. Kirk recommends that as a root-canal dressing, its use should be strictly confined to those cases where pericemental inflammation is not a present factor, as it does not possess antiseptic qualities sufficiently powerful to overcome quickly septic conditions due to the putrefactive changes common in root-canals. He also finds it extremely valuable in connection with gutta percha, as an antiseptic in conjunction with permanent root fillings - aristol with chloroform being used to dissolve the gutta percha. It is also recommended as an ingredient of nerve paste, being equal to iodoform for such a purpose, but free from the disagreeable odor of the latter substance; it is also used in chloroform solution, instead of sandarach varnish, for saturating cotton used for wedges or temporary fillings for retaining medicaments in cavities in the teeth; such a dressing or wedge may be retained for days or a week, and being antiseptic, it is free from disagreeable odor during that time. Aristol is also recommended as a dressing where approximal caries has extended beyond the gum margin, and where hypertrophy of the gum festoon occurs to the degree of forming a polypoid growth which invades the cavity ; also in the form of a varnish it is combined with collodion as a pulp-capping material. To increase the adhesiveness of the aristol solution, a small quantity of Canada balsam may be added to it.

Dr. R. M. Chase recommends an aristol chloro-percha root filling composed of two grains of aristol in one drachm of chloro-percha.

For Alveolar Abscess and Necrosed Teeth.

Dr. S. Clippinger.

Aristol.......

Chloroformi.....

01. Cassise.....

Signa

Apply on cotton wrapped around a small broach.

Signa 678Signa 679

For Ulcers, Burns, Eczema, etc. Dr. Potter.

Aristol......gr.v

Etheris......

Alcoholis ....

Saponis (soft) . . Signa. - Use as a liniment.

Dissolve the aristol in the ether and alcohol and then incorporate the soap.

Signa 680Signa 681

Arnica. leopard's bane.

Source

Arnica Montana is a perennial herbaceous plant of which the dried flowers and root - Arnica Flores and Arnica Radix - are the medicinal portions, and is found in the mountains of Northern Europe and the Northwestern portions of America.

Medical Properties And Action

Arnica is nervine, stimulant, and diaphoretic. In over-doses it is an acro-narcotic poison, causing vomiting, purging, vertigo, tetanic twitching of the muscles, and convulsions. Moderate doses, when long continued, are liable to cause a very troublesome eruption. Its activity depends upon an alkaloid - Arnicina, which is a bitter and acrid extractive.

Therapeutic Uses

Arnica is administered internally in typhus and typhoid fevers, chronic dysentery, rheumatic gout, etc., etc. Externally to bruises, sprains, lacerations, chilblains, etc., in the form of tincture - Tinctura Arnica. The antidote for poison by arnica is common vinegar.

Dose

Of the extract of arnica, gr. v to gr. x. Of the tincture of arnica (arnica root

Dose 682

rectified spirit Oj), the dose is

Dose 683

to

Dose 684

Dental Uses

In dental practice, the tincture of arnica is applied to irritable pulps of teeth, in periodontitis to prevent suppuration, to wounds of the mucous membrane of the mouth, combined with glycerine, to abraded surfaces caused by artificial teeth, and with tannic acid or glycerine of tannin for ulcers of the mouth.

The tincture of arnica, when largely diluted with water, forms an efficient mouth wash during operations upon the teeth. Equal parts of tincture of arnica and glycerine diluted with water form an effective mouth wash in inflammations of the mucous membrane of the mouth.

Dental Formulae

For Abraded Surfaces of the Mucous Membrane of the Mouth.

Tincturae arnicae, Glycerini .... Signa. - To be used as a lotion.

Astringent Mouth Wash in Alveolar Pyorrhoea, etc. Dr. J. R. Bell. Tincturae arnicae . . Acidi Carbolici . . Tincturae myrrhae . . Olei gaultheriae . . Alcoholis ....

Dental Formulae 685Dental Formulae 686Dental Formulae 687Dental Formulae 688

For Ecchymosis. Tincturae arnicae . . . Liquor ammonii muriat Aquae........

Signa

To be used as a lotion.

Signa 689Signa 690

For Inflamed and Ulcerated Mucous Membrane.

Tincturae arnicae . . .

Glycerini......

Aquae rosae.....

Aquae Destillatae . . .

Signa

To be used as a gargle.

Signa 691Signa 692