The following is the mode advised by Dr. Bigelow: - For straight incisions, of whatever length, provided the edges can be brought together without great difficulty, it is better to apply the solution in immediate contact with the skin as follows: - The bleeding should be arrested, and the skin thoroughly dried. If the lips of the wound are themselves in contact, the surgeon has only to apply a coating of the solution lengthwise over the approximated edges by means of a camel's-hair brush, leaving it untouched after the brush has passed over it until it is dry - a period varying from ten to twenty seconds. The first film will of itself have confined the edges together, but, in order to increase the firmness of the support, more must be applied in the same manner, allowing it to extend on either side of the incision half an inch or more. In some cases something more than a film of Collodion is required to counteract the tendency of the edges of the wound to separate. For this purpose goldbeater's skin or oil silk, which maintains the transparency of the dressing, should be applied to the wound after the solution has dried and firmly contracted. Lint or a piece of cloth or tissue paper, though not transparent, will answer. If, however, adhesion by first intention is not desired, the Collodion may be laid on transversely like strips of plaster, and one strip should be dried and have the support of goldbeater's skin. before a second is applied. Room is thus left for the escape of pus, and for the surgeon to view the progress of the wound. Mr. Maynard observes that in most instances he has employed it with straps of cotton and sheep-skin, forming with them a strong unyielding adhesive dressing, the best form in his opinion which can be employed in Surgery.

* Med. Time's, vol. xviii. p. 321.

Companion to the British Pharmacopia, p. 64.

These are the principal points of notice of any importance, but the reader may consult for further information the " London Journal of Medicine," Feb. 1849 (from which the above is condensed), "American Journal of Medical Sciences," April 1848, "Lancet," 1848-9, "Med. Times," Dec. 23rd, 1848, " Medical Gazette," &c. It is, however, not so universally applicable as was at first supposed; indeed, Mr. Startin states that in some cases it was found prejudicial (R)

941. Therapeutic Uses

Diseases of the Skin. In Chronic Erythema of the Face, Intertrigo, Herpes, Labialis, Herpes PrAe-putialis, Lichen Agrius, Lupus Exedens, Lupus Non exedens, Acne Vulgaris, and in some other cutaneous affections, Collodion has been employed by Erasmus Wilson,* and he states that he found it efficacious in the majority of cases.

942. To prevent Pitting in Small-Pox, the local application of Collodion was advised by Dr. Ranking, of Norwich. Its practical utility has been proved by M. Aran. Dr. Fenger,§ of Copenhagen, has proposed, as very effectual, the abortive treatment of Herpes Zoster, by the local application of Collodion.