This section is from the book "A Practitioner's Handbook Of Materia Medica And Therapeutics", by Thos. S. Blair. Also available from Amazon: A Practitioner's handbook of Materia Medica and Therapeutics.
Aloes And Aloin enter into many cathartic formulae, and, very properly, are rarely prescribed in large doses in an uncombined state. The average single dose of aloes is 4 grains, and of aloin I grain.
In small doses (1-10 gr. granules of aloin) it is useful in re-establishing physiologic equilibrium in overdosed persons who insist upon taking medicine. Useful in portal congestions and the troubles of phlegmatic beer drinkers and persons who overload themselves with starchy food and sweets. In still smaller doses it will often relieve a sense of insecurity in the rectum, but quite as often fails to do so.