Pilulae (Pills)

Solid bodies, usually spherical or oval, containing medicinal agents, and intended to be swallowed whole. A mass of the consistence of firm clay is made by beating medicaments together in a mortar. This mass is, with a machine, divided up and rolled into pills. In order that they may not possess a disagreeable taste, they are varnished, gilded, or sugar-coated. Unless the constituents are very heavy, each pill should not exceed 5 grains .30 gm. in weight, and the smaller they are the better. Soap, mucilage of acacia or tragacanth, and confection of rose are common excipients for pills. Glycerin is often added, for it attracts moisture and prevents the pill from getting hard, but pills made of it alone are too soft. Soap is useful for creosote and for essential oils if calcium phosphate and wheaten flour be added. Liquorice powder is a good absorbent. All pills are useless unless so made that they will dissolve in the gastro-intestinal canal. If it is required that they should not be acted upon until they reach the intestine they should be coated with keratin. Pills except when sugar- or gelatin-coated are often kept in some powder, as lycopodium, to prevent their sticking together. The pills in the U. S. P. are:

Dost.

Pilulae Phosphori . .

1/100 gr.; .00065 gm. in each.

1 gr.; .065 gm. in each.

3 gr.; .20 gm. in each.

1 pill.

- Opii ....

- Asafoetidae . .

1 - 2 pills.

- Ferri Iodidi...............

- Catharticae Composite ...

1 - 3 pills.

- Antimonii " ...

- Aloes et Mastiches ....

- Rhei Compositae.................................

Pilulae Aloes .........................

Dose.

- Aloes et Ferri .....................

1 - 4 pills.

- Rhei ...................................

1 - 5 pills.

- Catbarticae Vegetabiles . . .

- Ferri Carbonatis ....................

- Aloes et Asafoetidae . . .

- Aloes at Myrrhae ......................

2 - 10 pills.

Pulveres (Powders)

Preparations consisting of finely-powdered drugs, or (compound powders) mixtures of the same, and frequently consisting in part of a suitable diluent or ex-cipient. The best diluent for powders is sugar of milk, because of its hardness and comparative insolubility. The powders of the U. S. P. are:

Dose.

Pulvis Antimonialis.....

1/2 - 2 gr.; .03 - .12 gm.

- Ipecacuanhae et Opii . . .

3 - 15 gr.; .20 - 1.00 gm.

- Morphinae Compositus . . .

5 - 15 gr.; .30 - 1.00 gm.

- Cretae " ...

5 - 60 gr.; .30 - 4.00 gm.

- Aromaticus......

10 - 30 gr.; .60 - 2.00 gm.

- Jalapae Compositus ....

1/4 - 1 Pulveres Powders 88 ; 1.00 - 4.00 gm.

- Rhei " ....

1/2 - 1 Pulveres Powders 89 ; 2.00 - 4.00 gm.

- Glycyrrhizae " ...

1/2 - 2 Pulveres Powders 90 ; 2.00 - 8.00 gm.

For Pulvis Effervescens Compositus (Seidlitz Powder) see Sodium. Pulvis Ipecacuanhae et Opii is practically a trituration.