Action: Antiseptic. Improves condition of blood and stimulates all activity.

Chief use in pneumonia when patient becomes cyanotic due to imperfect oxygenation of the blood.

Pellotine, an alkaloid obtained from a Mexican plant and used in the form of the hydrochloride as a hypnotic.

Average dose, gr. ss.-0.03 Gm.

Pental is a hydrocarbon obtained from fusel oil as a colorless liquid and used as a general and local antiseptic. It is depressing.

Peronin is a hydrochloride of the benzyl ether of morphine, the action of which is between that of morphine and codeine. Average dose, gr. ss.-0.03 Gm.

Picric Acid, Trinitrophenol, an explosive combination of carbolic, sulphuric, and nitric acids, is official. It is a yellow, crystalline powder, soluble in water. Its action is antiseptic, astringent, and slightly irritant. Applied to suppurating burns through wet gauze it cleans and heals them readily. It should be applied thoroughly in all cases, the acid being removed frequently until the coagulated lymph covers the sore. It may also be applied to mucous membrane, in the form of a douche. It is sometimes rapidly absorbed and causes poisoning, the characteristic symptom being the yellow color of the skin, mucous membranes, and urine. Convulsions and collapse may occur.

Piperazine is a drug formed by the action of ammonia upon ethylene bromide. It is used as a diuretic, its active properties arising from its capacity for dissolving uric acid.

It is not irritant nor poisonous.

Average dose, gr. x.-0.3 in carbonated water.

Protargol

A silver compound containing 8.3% of metallic silver combined with protein. It is antiseptic, slightly astringent, non-irritant, and free from all caustic or corrosive effects, even on sensitive membranes. It is used in 1/4 to 2% solutions. It should be kept in amber vials.

Pyramidon is an amido derivative of antipyrin. It is milder, more gradual, and more lasting than antipyrin.

Average dose, gr. v.-0.3 Gm.

Pyrogallol

Pyrogallic acid is obtained by the action of heat on gallic acid. It is used in skin diseases as a local irritant, caustic, and parasiticide. It stains the skin and clothing brown. It is generally employed in the form of ointment or in flexible collodion. It may cause poisoning, manifested by headache, diarrhoea, chills, vomiting, a reddish color to the skin, dark brown urine, rapid heart and respiration, restlessness, convulsions, coma, and death. Official.

Salipyrin

This drug is the salicylate of antipyrin. It is considered an efficient antipyretic.

Average dose, gr. viii.-0.5 Gm.

Salophen is a derivative of salol, introduced as a substitute for the latter in order to avoid effects arising from the liberation of phenol in the organism, which occurs when salol is used. Its physiological actions are similar to those of salol.

Dose, gr. viii.-0.5 Gm.

Salvarsan, Called "606" or Arsenobenzol. - A complex organic arsenic salt put up for use. It is a yellow powder sealed in glass tubes.

Action: As a specific in syphilis, by destroying the organism, Spirocheta pallida, and neutralizing its poisons.

Administration: A suitable dilution of the drug in distilled water is administered by venous transfusion. Occasionally this solution is administered by deep injection into the muscles.

Average dose, gr. viii.-0.5 Gm.

The administration of the drug produces reaction of more or less severity in some cases. There may be a chill with accompanying high temperature. Blindness has resulted and the usual signs of arsenical poisoning may make their appearance.

Sanatogen is a combination of sodium-glycero-phos-phate and casein, used as a nutrient tonic.

Somatose is a preparation of meat in such a way as to be readily digestible, five parts of the preparation representing thirty parts of meat. Iron somatose and milk somatose are preparations with iron and from milk, respectively.

Somnal is made by the combination of chloral, alcohol, and urethan. It is a colorless liquid which will not mix with cold water, but dissolves in alcohol, or hot water. It is quite an efficient hypnotic, and usually prompt in its action. Its effects are considered less depressing than those of chloral, and more active than those of urethan.

Average dose,  xv.-I Gm., usually given in syrup of tolu.

"Stypticin," no longer so-called, is officially Cotarnine Hydrochloride. It is obtained from narcotin, one of the alkaloids of opium. It is given in solution, or in powder, wrapped in wafers, or best, in gelatine pearls. It may also be used hypodermically.

Average dose, gr. i.-0.06 Gm.

Taka-diastase is a starch-digesting ferment obtained from fungus grown on wheat bran. Average dose, gr. v.-0.3 Gm.

Tannalbin is a red brown product made by combining tannin and albumin, and used as an intestinal astringent. Average dose, gr. x-0.65 Gm.

Terebenum (Terebene) is a colorless liquid, of hot taste, obtained by chemical process from oil of turpentine. It is used as a stimulant expectorant. Official. Average dose,  iv.-0.25 mil, in an emulsion or in capsule.

Terpini Hydras, Terpin Hydrate (official), is made from turpentine but has no odor of turpentine. It is used as an expectorant.

Average dose, gr. iv.-0.25 Gm., given in tablets or syrup.

Terpinol is an oily liquid, obtained by combining terpine and hydrochloric acid. It has the same stimulant and expectorant properties as terpin hydrate, and is used under similar circumstances. Average dose,  viii-0.5 mil.

Tetronal is a compound allied to sulphonal, and in general similar to trional.

Average dose, gr. viii-0.5 Gm.

Theophylline (official) formerly known by the name theocin. It is obtained from the teaplant and is also produced chemically. It has diuretic qualities. Average dose, gr. iv.-0.25 Gm.

Thymacetin is a derivative of thymol, and related to phenacetin. It is used as an analgesic and hypnotic. The after-effects are sometimes unpleasant. Average dose, gr. v.-0.3 Gm.

Thymol Iodide contains about 43% of iodine, and is used as a substitute for iodoform. It is not poisonous. It is official.

Trional, now officially Sulphonethylmethane, is chemically allied to sulphonal, and is given as a hypnotic, and also as an antihydrotic. When it is successfully given it produces a quiet sleep and a natural awakening, but if, after being given twice in succession, no results follow, it is useless to try it further. When it acts, it acts quickly, and sleep comes on within a short time. It is not given for more than five or six nights in succession, as it sometimes causes prostration. It is apt to accumulate in the blood, and to avoid this, mineral waters are taken in conjunction with it. It causes constipation, and this must be watched for and overcome. It is given in hot milk just before retiring.

Average dose, gr. xii.-0.75 Gm.

Tropococain is an alkaloid from a variety of coca, used lik cocaine as a local anaesthetic. It is very costly.

Tussol is anti-pyrinin-mandelate, and is used as an antispasmodic. Average dose, gr. i.-0.06 Gm.

Urotropin is now officially Hexamethylenamine and has lost its trade name. Formed by the action of formaldehyde and ammonia. It is a urinary antiseptic, sterilizing the urine by giving off some of its formaldehyde. It increases the flow of urine and the excretion of uric acid, the solution of the urates beginning within twenty-four hours after the ingestion of the drug.

Average dose, gr. iv.-0.25 Gm.

Veronal is a hypnotic which in excess may cause a rash, neuralgic pains, or loss of muscular control. Over-use induces constipation and diminishes excretion from the kidneys. Large doses have caused death.

Average dose, gr. iv.-0.25 Gm.